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AnnoTCM: An Annotation Tool for Multimodal Metabolite-Phenotype Integration in Decoding Bioactive Compounds of Traditional Chinese Medicine.

Analytical chemistry - 13 Jan 2026

Liang Xingyi, Cui Yixin, Tan Yanwei, Zhou Yang, Cao Xingzu, Wu Zhe, Feng Chunling, Wen Xiaodong, Xing Xudong, Yang Hua

Abstract excerpt

Despite decades of pharmacological interest, the systematic identification of bioactive compounds in natural products (NPs) and traditional Chinese medicines (TCMs) remains constrained by the chemical complexity of herbal formulations and the absence of scalable tools to link chemical features with functional phenotypes. The field of drug discovery based on TCMs is a complex area of research that necessitates...

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PMID: 41396966
DOI: 10.1021/acs.analchem.5c04126

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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