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Article

Diversity in chemosensory receptor genes in dogs and wolves: degeneration of the olfactory receptor gene repertoire in the brachycephalic Pug.

Chemical senses - 22 Jan 2025

Inoue Hyuga, Gibbs Matthew, McGrane Scott J, Niimura Yoshihito

Abstract excerpt

Dogs, domesticated from gray wolves over 15,000 yr ago, exhibit extensive variation among breeds, including differences in olfactory ability. To investigate the genetic basis of these differences, we analyzed single-nucleotide variants (SNVs) in 3 chemosensory receptor gene families-olfactory receptors (ORs), vomeronasal receptors type 1 (V1Rs), and bitter taste receptors (T2Rs)-using whole-genome data from the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41395915
DOI: 10.1093/chemse/bjaf062
PMCID: PMC12703715

Genes

OR7D4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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