Article
Genetic alterations and aberrant hormonal pathways in thymic epithelial tumors.
BMC cancer - 12 Dec 2025
Zhang Yuqi, Lian Wenxin, Zuo Wenyan, Wang Fufeng, Zhang Yaru, He Jing, Wang Yan, Gao Wen
Abstract excerpt
BACKGROUND: Patients with thymic epithelial tumors (TETs) frequently show coexistence of various paraneoplastic syndromes, which severely affect their survival. Moreover, there is a lack of effective clinical treatment strategies for patients with unresectable metastatic and recurrent TETs. METHODS: To explore the genetic alterations that play a key role in the pathogenesis of TETs, we analyzed the whole-exome...
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