Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Double-stranded sperm DNA fragmentation assessed using comet assay is associated with recurrent pregnancy loss

5 Aug 2025

Abstract excerpt

RESEARCH QUESTION: Do men attending a recurrent miscarriage clinic have high double-stranded sperm DNA damage compared with a sperm donor population? DESIGN: This prospective cohort study included 100 men attending a recurrent miscarriage clinic, and 81 sperm donors from a European sperm bank who had proven fertility. All semen samples were evaluated using the Examen Lab alkaline (Exact) comet assay, which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Reproductive Biology and Fertility
Share to Reproductive System and Pregnancy
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 41371000
DOI: 10.1016/j.rbmo.2025.105184

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Double-stranded sperm DNA fragmentation assessed using comet assay is associated with recurrent pregnancy lossPMID 41371000Read ↗

Double Stranded Sperm DNA Breaks, Measured by Comet Assay, Are Associated with Unexplained Recurrent Miscarriage in Couples without a Female FactorSemantic proximity Read ↗

Sperm DNA fragmentation abnormalities in men from couples with a history of recurrent miscarriageSemantic proximity Read ↗

Human semen cryopreservation: a sperm DNA fragmentation study with alkaline and neutral Comet assaySemantic proximity Read ↗

Novel use of COMET parameters of sperm DNA damage may increase its utility to diagnose male infertility and predict live births following both IVF and ICSISemantic proximity Read ↗

Comprehensive analysis of sperm DNA fragmentation by five different assays: TUNEL assay, SCSA, SCD test and alkaline and neutral Comet assaySemantic proximity Read ↗

Sperm DNA damage output parameters measured by the alkaline Comet assay and their importanceSemantic proximity Read ↗

Using the alkaline comet assay in prognostic tests for male infertility and assisted reproductive technology outcomesSemantic proximity Read ↗

Sperm DNA fragmentation and idiopathic recurrent pregnancy loss: Results from a multicenter case–control studySemantic proximity Read ↗

Alkaline and neutral Comet assay profiles of sperm DNA damage in clinical groupsSemantic proximity Read ↗

Diagnostic Accuracies of the TUNEL, SCD, and Comet Based Sperm DNA Fragmentation Assays for Male Infertility: a Meta-analysis StudySemantic proximity Read ↗

Impact of sperm DNA fragmentation in couples with unexplained recurrent pregnancy loss: A cross‐sectional studySemantic proximity Read ↗

Sperm DNA damage measured by the alkaline Comet assay as an independent predictor of male infertility and in vitro fertilization successSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.