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Article

Improving radiomics-based isocitrate dehydrogenase 1 prediction in glioma patients using semi-supervised machine learning models.

BMC medical imaging - 9 Dec 2025

Ahmadzadeh Amir Mahmoud, Jafarnezhad Amirhossein, Elyassirad Danial, Vatanparast Mahsa, Gheiji Benyamin, Faghani Shahriar

Abstract excerpt

BACKGROUND: Determining isocitrate dehydrogenase (IDH) mutation status in glioma is important for determining prognosis. We aimed to compare supervised and semi-supervised machine learning (ML) models in glioma IDH1 mutation status prediction using magnetic resonance imaging (MRI)-derived radiomics features. METHODS: Images and segmentation masks from several public collections, including ACRIN-FMISO, CPTAC-GBM,...

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Identifiers

PMID: 41366330
DOI: 10.1186/s12880-025-02040-1
PMCID: PMC12802325

Genes

IDH1

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