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Article

Genetic and epigenetic regulatory networks in atrioventricular block: mechanisms and therapeutic prospects.

Epigenomics - 1 Dec 2025

Yan Song, Xia Yuting, Liu Jin, Zhang Yang, Wei Li

Abstract excerpt

Atrioventricular block (AVB) is a frequent arrhythmia and can arise from both genetic predisposition and epigenetic regulation. This review provides a synopsis of the latest findings concerning the interactions of genetic-epigenetic interactions with an emphasis on mechanisms that are most likely responsible for pathobiological pathways relating to the cause of AVB. For instance, hypermethylation of the SCN5A...

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Identifiers

PMID: 41363286
DOI: 10.1080/17501911.2025.2593426
PMCID: PMC12826716

Genes

SCN5A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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