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The enzyme OsDHFR-TS1 controls leaf senescence during grain filling via folate-dependent chlorophyll biosynthesis in rice.

Plant physiology - 2 Mar 2026

Xiao Yongkang, Wang San, Shu Hao, Zhang Hongshan, Guo Jia, Yang Xiaorong, Liu Yue, Ma Xinxin, Chen Congping, Ye Chaoqing, Deng Jiahao, Jiang Siqi, Jiang Yi, Yang Bin, Sun Changhui, Deng Xiaojian, Wang Pingrong

Abstract excerpt

Dihydrofolate reductase-thymidylate synthase (DHFR-TS) is a bifunctional enzyme that catalyzes the conversion of dihydrofolate (DHF) into tetrahydrofolate (THF) by the DHFR domain and dUMP to dTMP as well as 5,10-methylene-THF to DHF by the TS domain. To date, the contributions of DHFR-TS to chlorophyll biosynthesis and plant growth are not well defined. In this study, we isolated a grain-filling-stage premature...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41351358
DOI: 10.1093/plphys/kiaf629

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DHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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