JAK2 wild-type erythrocytosis: concept, differential diagnosis, diagnostic steps, and treatment approaches.

Abstract excerpt

JAK2 unmutated/wild-type erythrocytosis is a prevalent condition encompassing a wide spectrum of hereditary and acquired entities. It is conventionally defined by the same hemoglobin/hematocrit thresholds as for polycythemia vera. Incidence has been reported to be between 0.13% and 4.1%. The most clinically relevant step in the workup of erythrocytosis is the exclusion of polycythemia vera through JAK2 mutation...

Topics

• Humans
• Polycythemia
• Janus Kinase 2
• Diagnosis, Differential
• Mutation
• Erythropoietin
• Polycythemia Vera