Article
Association between GRIK1 rs363598 and intergenic rs360932 variants and susceptibility to autism spectrum disorders in Egyptian children.
BMC pediatrics - 1 Dec 2025
Bassiony Heba, Baiomy Ahmed, Ahmed Doaa, Elaraby Nesma M, Ammar Tamer H A, Ashaat Engy A
Abstract excerpt
BACKGROUND: Autism spectrum disorder (ASD) is a genetically inherited, complex neuropsychiatric developmental condition that impacts a person's ability to learn, interact, and communicate. ASD is currently classified as a heterogeneous disorder, given that the pathophysiology of ASD is yet unknown. The GRIK gene family (GRIK1, GRIK2, GRIK3, GRIK4, and GRIK5) has genetic variants associated with many psychiatric...
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