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Article

Rapid Phenotypic Antimicrobial Susceptibility Testing with Multichannel Large-Volume Scattering Imaging and a Bayesian Gaussian Process Model.

Analytical chemistry - 9 Dec 2025

Jiang Jiapei, Zhou Shuang, McBride Michelle, Haller Yannik, Williams Timothy, Jing Tianwei, Ly Nguyen, Hernandez Isabelle, Haydel Shelley E, Wang Shaopeng

Abstract excerpt

Multidrug-resistant (MDR) bacterial infections present a great challenge to healthcare, particularly during life-threatening conditions, such as septic shock. In these critical cases, testing delays are life-threatening, as patient mortality increases by 7.6% for each hour without effective antibiotics. To overcome these issues, we have developed a multichannel Large-Volume Scattering imaging (LVSim) system for...

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Identifiers

PMID: 41321146
DOI: 10.1021/acs.analchem.5c04615
PMCID: PMC12774859

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