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Multiplexed, rapid phenotypic antibiotic susceptibility testing based on angle-resolved light scattering imaging of microfluidic droplets.

Journal of advanced research - 1 Jun 2026

Graf Martina, Sarkar Arjun, Svensson Carl-Magnus, Munser Anne-Sophie, Schröder Sven, Müller Elke, Hengoju Sundar, Figge Marc Thilo, Rosenbaum Miriam A

Abstract excerpt

INTRODUCTION: There is an urgent need for rapid, high-throughput phenotypic antimicrobial susceptibility testing (AST) capable of assessing a microbial sample's susceptibility to multiple antibiotics. OBJECTIVES: In this study, we have established a multiplexed rapid AST platform that employs droplet microfluidics for high-throughput single-cell based analysis, 2D angle-resolved light scattering for growth...

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Anti-Bacterial Agents
Microbial Sensitivity Tests
Microfluidic Analytical Techniques
Microfluidics
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Scattering, Radiation

Staphylococcus aureus

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Identifiers

PMID: 41015176
DOI: 10.1016/j.jare.2025.09.047
PMCID: PMC13227228

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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