Association of IL-1β Gene Polymorphism with Prostate Cancer Severity, Prostate Volume, and PSA Levels: A Case-Control Study.

doi:10.31557/APJCP.2025.26.11.4139

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Article

Association of IL-1β Gene Polymorphism with Prostate Cancer Severity, Prostate Volume, and PSA Levels: A Case-Control Study.

Asian Pacific journal of cancer prevention : APJCP - 1 Nov 2025

Ismael Ayad Abdulkhaleq, Hussein Ahmed Mahmood, Saber Alan Adnan

Abstract excerpt

BACKGROUND: Prostate cancer (PCa) is the second leading cause of death from cancer among men. The development of prostate cancer depends on chronic inflammation and cytokines, including interleukin-1 beta (IL-1β). The objective of the research was to test the association between SNP (rs16944) in interleukin-1 β (IL-1β) gene and serum levels of Prostate Specific Antigen (PSA) and testosterone concentrations in...

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Identifiers

PMID: 41312941
DOI: 10.31557/APJCP.2025.26.11.4139
PMCID: PMC12948177

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