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Article

Long QT syndrome type 1: clinical and functional characterization of KCNQ1 variant c.1111G > C.

BMC cardiovascular disorders - 26 Nov 2025

Bileisiene Neringa, Shelest Anastasiia, Petraityte Gunda, Alaburda Aidas, Sasnauskiene Ausra, Jasinevicius Andrius, Kairys Visvaldas, Dapkunas Justas, Mikstiene Violeta, Zitkute Vilmante, Maldziene Zivile, Barysiene Jurate, Preiksaitiene Egle

Abstract excerpt

BACKGROUND: Congenital long QT syndrome is a clinical disorder of genetic origin characterized by delayed repolarization of the myocardium, electrocardiographic QT prolongation, and increased risk of syncope, and sudden cardiac death due to polymorphic ventricular tachycardia. KCNQ1-related congenital long QT syndrome (LQT1) is the most prevalent of the long QT syndrome genetic subgroups and is typically caused...

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Source

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Identifiers

PMID: 41299264
DOI: 10.1186/s12872-025-05335-x
PMCID: PMC12659328

Genes

KCNQ1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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