Dietary Intervention for Systemic Lupus Erythematosus patients based on HLA-DQ2 and DQ8 genotyping (DISH): a protocol for a randomised controlled study.

doi:10.1136/lupus-2025-001833

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Article

Dietary Intervention for Systemic Lupus Erythematosus patients based on HLA-DQ2 and DQ8 genotyping (DISH): a protocol for a randomised controlled study.

Lupus science & medicine - 24 Nov 2025

Widhani Alvina, Wardhani Wahyu Ika, Shahab Selvi Nafisa, Kasih Mentari, Cahyanur Rahmat, Yunihastuti Evy, Ahani Ardhi Rahman

Abstract excerpt

INTRODUCTION: SLE is a chronic autoimmune disease that is influenced by both genetic and environmental factors, one of which is diet. Dietary intervention plays a role in the management of SLE, and precision nutrition based on genetic data may enhance its effectiveness. The human leukocyte antigen (HLA)-DQ2 and DQ8 genotypes are strongly associated with coeliac disease (CD), and emerging evidence suggests a...

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Topics

Humans
HLA-DQ Antigens
Lupus Erythematosus, Systemic
Quality of Life
Genotype
Adult

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Female

Diet, Gluten-Free

Randomized Controlled Trials as Topic

Male

Celiac Disease

Middle Aged

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 41290265
DOI: 10.1136/lupus-2025-001833
PMCID: PMC12645617

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