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ACSM5 c.1273 C> A Polymorphism Promotes Malignant Progression of Lung Adenocarcinoma in Xuanwei Region.

Applied biochemistry and biotechnology - 1 Feb 2026

He Chenglu, Zhang Hui, Wang Xiao, Zhong Min, Shi Hongqiong, Li Ya, Duan Yong

Abstract excerpt

Lung adenocarcinoma (LUAD) is highly prevalent in Xuanwei region, Yunnan, China, but little is known about the genetic basis of this regional cancer. In our study, by performing the transcriptome sequencing and exome sequencing of Xuanwei LUAD and expression quantitative trait loci (eQTL) analysis, ACSM5 c.1273 C> A variant was identified as the top polymorphism affecting the highest number of downstream genes in...

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PMID: 41273635
DOI: 10.1007/s12010-025-05457-0

Genes

ACSM5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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