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Next-generation Sequencing Reveals Age-dependent Genetic Underpinnings in Lung adenocarcinoma

1 Jan 2022

Abstract excerpt

Background: More than 40% of lung cancer patients are diagnosed at ages over 70. However, the genomic and clinical characteristics among them remain elusive. Here, we performed targeted capture sequence to characterize the mutational spectrum of Chinese lung adenocarcinoma (LUAD) patients across ages. Patients and Methods: 2025 LUAD patients were divided into three groups: young (50 years old) (n=416, 20.54%),...

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PMID: 35371328
DOI: 10.7150/jca.65370

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