Article
Advancing the understanding of age-specific phenotypes in childhood-onset takayasu arteritis.
Pediatric research - 1 Jun 2026
Saad Khaled, Hussain Soha A, Ahmad Ahmad Roshdy, Elfarargy Mohamed Shawky, Elhoufey Amira, Alhasan Khalid A, Temsah Mohamad-Hani, Embaby Mostafa M
Abstract excerpt
IMPACT: Childhood-onset Takayasu arteritis (cTAK) is not a uniform disease but exhibits distinct age-specific clinical and vascular phenotypes across developmental stages, from infants to adolescents. These differences necessitate age-tailored diagnostic approaches and therapeutic strategies to improve outcomes and reduce treatment-related morbidity. The concept of "developmental vasculopathy" links vascular...
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