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Predictive Utility of Genetic Risk for Myopic Maculopathy Presence and Progression in a Chinese High Myopia Cohort.

Investigative ophthalmology & visual science - 3 Nov 2025

Li Zhixi, Zhao Ziyi, Zhang Kai, Jiang Feng, Xie Liqiong, He Mingguang

Abstract excerpt

Purpose: To evaluate the predictive utility of genetic risk for predicting the presence and longitudinal progression of myopic maculopathy among Chinese pediatric and adult high myopia cohorts. Methods: Highly myopic participants (n = 623, spherical equivalence [SE] <-6.00 diopters [D]) were recruited from 2011 to 2012 and followed up with 2-year intervals. Multivariate logistic regression models and...

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Identifiers

PMID: 41247131
DOI: 10.1167/iovs.66.14.38
PMCID: PMC12633768

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