Determination of the Frequency of HBB (c.20 A > T) Gene Mutation in the Nigerian and Zimbabwean Populations in Northern Cyprus.

Abstract excerpt

Sickle cell disease (SCD) is one of the most frequently observed monogenic diseases and is a major health problem worldwide. It is particularly prevalent in some countries such as Africa, the Middle East and the Mediterranean region. Due to a single point mutation in the β-globin gene HBB (c.20 A > T), the glutamic acid is replaced by valine amino acid at the sixth position of the β-globin chain (p.Glu6Val),...

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• Anemia, Sickle Cell
• beta-Globins
• Black People
• Cyprus
• Gene Frequency