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Article

Contribution of intestinal barrier damage, microbial translocation and HIV-1 infection status to an inflammaging signature.

PloS one - 1 Jan 2014

Steele Amanda K, Lee Eric J, Vestal Brian, Hecht Daniel, Dong Zachary, Rapaport Eric, Koeppe John, Campbell Thomas B, Wilson Cara C

Abstract excerpt

BACKGROUND: Systemic inflammation is a characteristic of both HIV-1 infection and aging ("inflammaging"). Intestinal epithelial barrier damage (IEBD) and microbial translocation (MT) contribute to HIV-associated inflammation, but their impact on inflammaging remains unclear. METHODS: Plasma biomarkers for IEBD (iFABP), MT (LPS, sCD14), T-cell activation (sCD27), and inflammation (hsCRP, IL-6) were measured in 88...

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Source

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Identifiers

PMID: 24819230
DOI: 10.1371/journal.pone.0097171
PMCID: PMC4018269

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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