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Article

Genetic susceptibility to necrotizing enterocolitis in very preterm infants: evidence from twin data.

Pediatric research - 1 Jun 2026

Bai Ruimiao, Chen Xiang, Jiang Siyuan, Mo Yan, Qian Aimin, Cao Yun, Du Lizhong, Lee Shoo Kim, Hu LiYuan, Yang Jie, Li Yajun, Lei Xiaoping, Luo Lijuan, Zhou Wenhao

Abstract excerpt

BACKGROUND: Necrotising enterocolitis (NEC) is a significant complication for very preterm infants (VPIs). The role of genetic predisposition in the development of NEC among VPIs has not been firmly established. This study aimed to explore the heritability factors in NEC among VPIs. METHODS: A retrospective cohort study was conducted on 4138 infants from 2069 twin pairs. Twins were categorised based on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 41214289
DOI: 10.1038/s41390-025-04536-6

Genes

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