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Article

The role of vitamin D receptor gene polymorphism in the development of necrotizing enterocolitis.

Pediatric research - 1 Jul 2023

Barut Dogan, Akisu Mete, Koroglu Ozge Altun, Terek Demet, Ergin Firat, Onay Huseyin, Yalaz Mehmet, Kultursay Nilgun

Abstract excerpt

BACKGROUND: Vitamin D and its receptor (VDR) effects on the gastrointestinal system are among its most critical multisystemic effects. METHODS: This study aimed to reveal that VDR gene polymorphisms may constitute a risk factor for necrotizing enterocolitis (NEC). VDR Fok1-Bsm1-Apa single-nucleotide polymorphisms were analyzed in the NEC group (n = 74) and the control group (n = 147). Among 1112 babies at and...

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Identifiers

PMID: 36596941
DOI: 10.1038/s41390-022-02426-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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