Role of Heritable and Environmental Contributions to the Development of Severe Intraventricular Hemorrhage in Very Preterm Infants: Results from a Multicenter Twins Cohort Study.

Abstract excerpt

INTRODUCTION: Severe intraventricular hemorrhage (sIVH) remains a significant complication for very preterm infants (VPIs). This study aimed to assess heritable and environmental contributions to sIVH. METHODS: A total of 2,074 twin pairs born at gestational age <32 weeks with known sIVH status were identified. Three statistical methods were applied, including the Pearson χ2 test, intra-class correlation (ICC),...

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