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Genomic Instability in Hereditary Breast Cancer: Clinical and Nursing Implications for Risk Assessment and Targeted Therapeutic Strategies.

Seminars in oncology nursing - 1 Apr 2026

Alloubani Aladeen, Nimer Refat, Farhan Fatima, Eid Farah, Khawaja Yahya

Abstract excerpt

OBJECTIVES: This review aims to bridge genomic insights with oncology nursing practice, promoting risk-informed care for patients with hereditary breast cancer (HBC). METHODS: This study reviewed publications from 2018 to 2024, searching PubMed, CINAHL, and Cochrane under PRISMA guidelines. It systematically reviews GI, emphasizing sporadic and hereditary breast cancer (BC), including BRCA1/2-related hereditary...

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Breast Neoplasms
BCL2 gene
BRCA1 gene
TP53 gene
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Testing

Genomic Instability

Risk Assessment

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Identifiers

PMID: 41207815
DOI: 10.1016/j.soncn.2025.152054

Genes

BCL2
BRCA1
TP53

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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