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Article

Interchromosomal linkage disequilibrium analysis reveals strong indications of sign epistasis in wheat breeding families.

G3 (Bethesda, Md.) - 7 Jan 2026

Tessele Augusto, Morris Geoffrey, Akhunov Eduard, Johnson Blaine, Clinesmith Marshall, Hope Addison Carroll, Fritz Allan

Abstract excerpt

Additive gene action is assumed to underlie quantitative traits, but the eventual poor performance of elite wheat lines as parents suggests that epistasis could be the underlying genetic architecture. Sign epistasis is characterized by alleles having either a beneficial or detrimental effect depending on the genetic background, which can result in elite lines that fail as parents in certain parental combinations....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41206220
DOI: 10.1093/g3journal/jkaf265
PMCID: PMC12774603

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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