The combined association between sleep duration and insomnia symptoms with dementia and cognitive deficits: a multivariable-adjusted and genetic liability study.

Abstract excerpt

Insomnia symptoms in combination with extreme habitual sleep durations may be associated with long-term dementia incidence, which we explored using multivariable-adjusted regression and genetic association analyses in Europeans. European-ancestry participants free of baseline dementia (N = 422,106; 5288 new cases over 12.7 years follow-up) from UK Biobank were stratified into six groups based on the combination...

Topics

• Humans
• Sleep Duration
• Sleep Initiation and Maintenance Disorders
• Female
• Male
• Dementia