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Article

CKS2 promotes the malignant phenotypes of bladder cancer cells via PI3K/AKT signaling pathway activation.

Cell cycle (Georgetown, Tex.) - 1 Jan 2025

Yang Tao, Kong Shao-Peng, Xu Qing-Le, Zhan Cheng-Xin, Wang Xiao-Tong, Li Shou-Bin, Wang Gang, Ma Jian-Guo

Abstract excerpt

Cyclin-dependent kinase subunit 2 (CKS2) has been implicated in various malignancies. This study investigates the mechanism by which CKS2 contributes to bladder cancer (BC) progression. Abnormally expressed genes were identified by differential analysis of tumor and normal tissues using Gene Expression Omnibus datasets. Subsequently, functional assays - including cell proliferation, Transwell migration, colony...

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Identifiers

PMID: 41200902
DOI: 10.1080/15384101.2025.2586117
PMCID: PMC12918319

Genes

PTEN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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