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Article

Contribution of fibroblasts to tunnel formation and inflammation in hidradenitis suppurativa/ acne inversa

29 May 2019

Abstract excerpt

The precise pathogenic mechanisms in the development, persistence and worsening of hidradenitis suppurativa (HS) remain ill-defined. This chronic inflammatory dermatosis displays a strong Th1 and Th17 inflammatory signature with elevated levels of TNF-α, IL-1β, IL-17 and IFNγ in lesional and perilesional tissue. HS significantly differs to other chronic inflammatory dermatoses due to the development of...

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PMID: 31140657
DOI: 10.1111/exd.13978

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