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Article

Cascade testing in an ovarian cancer traceback genetic testing program: The GRACE study experience.

Journal of genetic counseling - 1 Dec 2025

Zepp Jamilyn M, Feigelson Heather S, Prado Yolanda K, Reyes Ana A, Rope Alan F, Sawyer Jennifer K, Weinmann Sheila, White Larissa L, Hunter Jessica Ezzell, Henrikson Nora B

Abstract excerpt

Approximately 20% of individuals diagnosed with ovarian cancer (OC) have an inherited pathogenic or likely pathogenic variant (P/LP) in a cancer risk gene. Though genetic testing for hereditary cancer risk is currently recommended at OC diagnosis, individuals who have not received risk information and their at-risk relatives (ARR) can benefit from genetic testing at any point. In a single-arm implementation...

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PMID: 41192449
DOI: 10.1002/jgc4.70133
PMCID: PMC13218544

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