Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prognostic implications of HER2 in ovarian cancer: Associations with homologous recombination deficiency and folate receptor alpha expression.

Gynecologic oncology - 1 Dec 2025

Park Junsik, Lee Dahye, Kim Soyeon, Kim Yoo-Na, Lee Yong Jae, Park Eunhyang, Kim Sunghoon, Lee Jung-Yun

Abstract excerpt

OBJECTIVE: We evaluated expression patterns of human epidermal growth factor receptor 2 (HER2) by histological subtype and key biomarkers in ovarian cancer (OC). METHODS: We retrospectively analyzed 441 patients with primary or recurrent OC who underwent HER2 immunohistochemistry (IHC) at Yonsei Cancer Center. Association between histological subtype, HER2 and folate receptor alpha (FRα) expression, BRCA1/2...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to BRCA1 Protein

Share to BRCA2 Protein

Share to Erb-b2 Receptor Tyrosine Kinases

Share to Homologous Recombination

Share to Ovarian Neoplasms

Share to Prognosis

Source

Identifiers

PMID: 41192265
DOI: 10.1016/j.ygyno.2025.10.029

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 11 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Prognostic implications of HER2 in ovarian cancer: Associations with homologous recombination deficiency and folate receptor alpha expression.PMID 41192265Read ↗

Folate receptor alpha protein expression in ovarian serous cystadenocarcinoma tumors of The Cancer Genome Atlas: exploration beyond single-agent therapySemantic proximity Read ↗

Spatial, Temporal, and Molecular Heterogeneity of ADC targets in High-Grade Serous Ovarian CarcinomaSemantic proximity Read ↗

Human epidermal growth factor receptor-2 expression and subsequent dynamic changes in patients with ovarian cancer.Semantic proximity Read ↗

Spatial, temporal, and molecular heterogeneity of ADC targets in high-grade serous ovarian carcinoma.Semantic proximity Read ↗

Predictive value of homologous recombination deficiency status for survival outcomes in primary tubo-ovarian high-grade serous carcinoma.Semantic proximity Read ↗

Moderate Immunohistochemical Expression of HER-2 (2+) Without <i>HER-2</i> Gene Amplification Is a Negative Prognostic Factor in Early Breast CancerSemantic proximity Read ↗

Folate Receptor Alpha in Advanced Epithelial Ovarian Cancer: Diagnostic Role and Therapeutic Implications of a Clinically Validated BiomarkerSemantic proximity Read ↗

RB1 expression and HR proficiency define a poor-outcome molecular subtype of high grade serous ovarian carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.