SPIROMICS HF: Rationale, Design, and Reproducibility of Measures.

doi:10.1161/CIRCHEARTFAILURE.125.012833

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Article

SPIROMICS HF: Rationale, Design, and Reproducibility of Measures.

Circulation. Heart failure - 1 Dec 2025

Barr R Graham, Lima Joao A C, Prince Martin R, Ambale-Venkatesh Bharath, Abraham Theodore, Agarwal Prachi P, Arora Garima, Balasubramanian Aparna, Barjaktarevic Igor, Bello Natalie A, Bluemke David A, Budoff Matthew J, Carr James C, Chaudhuri Dipayan, Cooper Christopher B, Couper David, Finn J Paul, Freed Benjamin H, Han MeiLan K, Hansel Nadia N, Hsu Jeffrey J, Kitzman Dalane W, Krishnan Jerry A, LaBounty Troy M, Lee Yoo Jin, Liu Jing, Lloyd Steven G, Markl Michael, Mukherjee Monica, Beussink-Nelson Lauren, Ohar Jill, Ortega Victor E, Paine Robert, Peters Stephen P, Schroeder Joyce D, Shen Wei, Shepshelovich Daniel, Sun Yifei, Vogel-Claussen Jens, Watson Karol E, Wells J Michael, Wieben Oliver, Woodruff Prescott G, Shah Sanjiv J

Abstract excerpt

BACKGROUND: Although chronic obstructive pulmonary disease (COPD) and heart failure with preserved ejection fraction often coexist with overlapping clinical features, they are usually studied separately. The SPIROMICS HF (Subpopulations and Intermediate Outcome Measures in COPD and Heart Failure Study) is testing hypotheses that new computed tomography emphysema subtypes are associated with specific...

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Identifiers

PMID: 41190426
DOI: 10.1161/CIRCHEARTFAILURE.125.012833
PMCID: PMC12888806

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