Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Global concerns, local challenges: the alarming spread of FC428-related gonococcal strains in Nanchang City, 2021.

BMC microbiology - 30 Oct 2025

Jiang Qinwen, Chen Wentao, Zhang Ran, Qi Yuqiu, Peng Hui, Tao Chen Long, Lu Songwei, Ke Qiankun, Shen Shangzhu, Wang Zhuo, Lin Xiaomian

Abstract excerpt

OBJECTIVES: Antimicrobial resistance (AMR) in N. gonorrhoeae is a major global health issue, with most ceftriaxone treatment failures linked to Asian strains, especially FC428-related strains. Since 2019, Nanchang City has participated in World Health Organization’s surveillance program, but local AMR assessments were lacking. This study aimed to examine the AMR profiles and molecular traits of N gonorrhoeae from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Azithromycin
Share to Ceftriaxone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cephalosporins

Share to Drug Resistance, Bacterial

Share to Gonorrhea

Share to Neisseria gonorrhoeae

Share to Penicillins

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 41168755
DOI: 10.1186/s12866-025-04448-9
PMCID: PMC12573974

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Global concerns, local challenges: the alarming spread of FC428-related gonococcal strains in Nanchang City, 2021.PMID 41168755Read ↗

Increase in Multidrug Resistant Neisseria gonorrhoeae FC428-Like Isolates Harboring the Mosaic penA 60.001 Gene, in Nanjing, China (2017-2020)Semantic proximity Read ↗

Antimicrobial Resistance Profiling and Genome Analysis of the penA-60.001 Neisseria gonorrhoeae Clinical Isolates in China in 2021Semantic proximity Read ↗

Identification of ceftriaxone-resistant Neisseria gonorrhoeae FC428 clone and isolates harboring a novel mosaic penA gene in Chengdu in 2019–2020Semantic proximity Read ↗

Molecular screening to track ceftriaxone-resistant FC428-like Neisseria gonorrhoeae strains’ dissemination in four provinces of China, 2019 to 2021Semantic proximity Read ↗

Sustained transmission of the ceftriaxone-resistant Neisseria gonorrhoeae FC428 clone in ChinaSemantic proximity Read ↗

High percentage of the ceftriaxone-resistantNeisseria gonorrhoeaeFC428 clone among isolates from a single hospital in Hangzhou, ChinaSemantic proximity Read ↗

Emergence of a predominant sequence type ST7363 and the increasing trend of resistance to cefixime and ceftriaxone in Neisseria gonorrhoeae in Southern Taiwan, 2019–2021Semantic proximity Read ↗

Characterization of a novel mosaic-like mtr operon and inter-regional transmission of dual-resistant Neisseria gonorrhoeae ST7363 sub-lineage in China.Semantic proximity Read ↗

First nationwide study regarding ceftriaxone resistance and molecular epidemiology of Neisseria gonorrhoeae in China.Semantic proximity Read ↗

High-level ceftriaxone resistance due to transfer of penA allele 60.001 into endemic gonococcal lineages in Hangzhou, China.Semantic proximity Read ↗

A Whole-genome Sequencing Analysis of Neisseria gonorrhoeae Isolates in China: An Observational StudySemantic proximity Read ↗

Ceftriaxone-resistant<i>Neisseria gonorrhoeae</i>detected in England, 2015 to 2024; an observational studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.