Article
High-level ceftriaxone resistance due to transfer of penA allele 60.001 into endemic gonococcal lineages in Hangzhou, China.
The Journal of antimicrobial chemotherapy - 4 Nov 2024
Yang Fan, Sun Xia, Fu Ying, Zhao Feng, Lin Xu'ai, Chen Yan, van der Veen Stijn
Abstract excerpt
OBJECTIVES: Neisseria gonorrhoeae strains associated with the high-level ceftriaxone-resistant FC428 clone or containing its main resistance determinant, penA allele 60.001, have shown global transmission. In Hangzhou, China, 10% of the isolates were associated with the FC428 clone in 2019. Here, we investigated ceftriaxone resistance and the prevalence of FC428-associated strains in Hangzhou in 2020-22. METHODS:...
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