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Development and Evaluation of a Web-Based Outcome Database for Advanced Melanoma with Rare BRAF Mutations.

Applied clinical informatics - 1 Oct 2025

Dugas-Breit Susanne, Menzer Christian, Blank Christian U, Carlino Matteo S, Lehmann Christoph U, Hassel Jessica C, Dugas Martin

Abstract excerpt

Rare B-rapidly accelerated fibrosarcoma gene (BRAF) mutations in advanced melanoma, and other malignancies, represent a significant clinical challenge due to sparse evidence on the efficiency of targeted therapy. Conventional genomic databases do not integrate detailed outcome data on treatments for patients with these mutations, requiring innovative informatics approaches.For the use case of patients with rare...

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Identifiers

PMID: 41167597
DOI: 10.1055/a-2717-3119
PMCID: PMC12575071

Genes

BRAF

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