No evidence of a causal relationship between negative emotions and glaucoma: evidence triangulation from genetic correlation, Mendelian randomisation and colocalisation.

Abstract excerpt

PURPOSE: Observational studies suggest that anxiety and depression disorders have significant correlation, but these results may have been influenced by confounding factors, and negative emotions that do not meet the criteria for clinical mental disease diagnosis are more common, the evidence for this association is unclear. This study employed whole-genome linkage disequilibrium score regression (LDSC),...

Topics

• Humans
• Mendelian Randomization Analysis
• Glaucoma
• Emotions
• Male
• Female
• Genome-Wide Association Study