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Article

Ribosome-engineered Lacticaseibacillus rhamnosus GG with enhanced adhesion and immune activation via surface moonlighting proteins.

Microbiology spectrum - 2 Dec 2025

Tsukagoshi Masami, Soyolmaa Jamiyanpurev, Nomoto Shunsaku, Namai Fu, Murakami Aito, Inoue Kazuma, Yoda Masahiro, Hibi Tomoyuki, Sato Takashi, Kinoshita Hideki, Shimosato Takeshi

Abstract excerpt

Commercial interest in using probiotics to enhance human health and animal production is growing. Accordingly, there is great demand for probiotic lactic acid bacteria exhibiting enhanced robustness and functionality. The present study focused on ribosome engineering (RE), a simple, economical, and safe non-genetically modified organism microbial breeding technology. Ribosome-engineered mutants of...

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Identifiers

PMID: 41143415
DOI: 10.1128/spectrum.02635-25
PMCID: PMC12671100

Genes

TNF
GAPDH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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