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Article

Prevalence of Candidate Vaccine Targets and Genomic Features of Pediatric Invasive Streptococcus Agalactiae in Japan.

The Journal of infectious diseases - 17 Jan 2026

Kasai Masashi, Nakano Satoshi, Koide Shota, Otake Shogo, Shibata Meiwa, Ishida-Kuroki Kasumi, Sugawara Yo, Akeda Yukihiro, Nozu Kandai, Sugai Motoyuki

Abstract excerpt

BACKGROUND: Streptococcus agalactiae (Group B Streptococcus, GBS) is a leading cause of invasive neonatal and infant infections, including sepsis and meningitis. This study aimed to estimate the vaccine coverage and characterize the genomic features of pediatric invasive GBS in Japan. METHODS: We conducted a nationwide, multicenter, retrospective genomic surveillance study involving 237 GBS isolates from sterile...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41065369
DOI: 10.1093/infdis/jiaf491
PMCID: PMC12811887

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