Comparative genomics of carbapenem-resistant Acinetobacter baumannii isolated from pediatric patients in a tertiary care hospital.

doi:10.1128/spectrum.01676-25

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Article

Comparative genomics of carbapenem-resistant Acinetobacter baumannii isolated from pediatric patients in a tertiary care hospital.

Microbiology spectrum - 4 Nov 2025

Guillén-Navarro Dafne, Ochoa Sara A, De La Rosa-Zamboni Daniela, Giono-Cerezo Silvia, Xicohtencatl-Cortes Juan, Cruz-Córdova Ariadnna

Abstract excerpt

Acinetobacter baumannii is a short gram-negative bacillus, notable for its intrinsic multidrug resistance and genomic plasticity, which facilitates the acquisition of additional resistance genes via mobile genetic elements. Due to its increasing carbapenem resistance, the World Health Organization has classified it as a critical priority pathogen. This study performed a comparative genomic analysis of 20...

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Topics

Acinetobacter baumannii
Humans
Carbapenems
Acinetobacter Infections
Tertiary Care Centers
Anti-Bacterial Agents

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genome, Bacterial

Multilocus Sequence Typing

Genomics

Drug Resistance, Multiple, Bacterial

Microbial Sensitivity Tests

Child

Mexico

Plasmids

Virulence

Polymorphism, Single Nucleotide

Infant

Virulence Factors

Source

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Identifiers

PMID: 41051204
DOI: 10.1128/spectrum.01676-25
PMCID: PMC12584756

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