Article
DROL1/DIB1 determines U5 snRNP specificity for intron terminal dinucleotide in Arabidopsis.
The Plant journal : for cell and molecular biology - 1 Sept 2025
Suzuki Takamasa, Niwa Tomoko, Furuta Ayami, Aramaki Daisuke, Toyama Kokone, Ito Mizuho, Kikuchi Rio, Ishikawa Sanetaka, Ohsumi Takeki, Inonue Tatsuki, Shiotani Yoshiaki, Ito Yuma, Inami Yuriko
Abstract excerpt
Most introns contain GT-AG terminal dinucleotides; although some eukaryotes have introns with AT-AC termini whose splicing is impaired in the Arabidopsis defective repression of OLE3::LUC 1 (drol1) mutant. We identified seven drol1 suppressors across four loci, all encoding subunits of the U5 snRNP. Although AT-AC splicing was partially restored in these suppressors, their phenotypes were almost completely...
Read the complete abstract on PubMedTopics
- Arabidopsis
- Arabidopsis Proteins
- Introns
- RNA Splicing
- Ribonucleoproteins, Small Nuclear