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Article

Investigation of the characteristics of LDLR gene rs688 polymorphism and its association with dyslipidemia in patients at high to very high cardiovascular risk.

BMC cardiovascular disorders - 26 Sept 2025

Sen Nguyen Thi Thu, Nga Pham Thi Ngoc, Toan Ngo Hoang, Kien Nguyen Trung

Abstract excerpt

BACKGROUND: The rs688 polymorphism in the LDLR gene has been linked to lipid profile alterations, yet its impact in patients at high to very high cardiovascular risk remains unclear. OBJECTIVES: To investigate the association between the LDLR rs688 polymorphism and dyslipidemia in high to very high cardiovascular risk patients. METHODS: This cross-sectional study included patients classified as high or very high...

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Identifiers

PMID: 41013249
DOI: 10.1186/s12872-025-05113-9
PMCID: PMC12465651

Genes

LDLR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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