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Genetic landscape of human oocyte/embryo defects

25 Sept 2025

Abstract excerpt

Oocyte/embryo defects can result in oocyte maturation arrest, fertilization failure, embryonic arrest, and infertility as well as recurrent in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) failures. However, the genetic determinants of human oocyte/embryo defects remain largely unknown, and the overall genetic diagnostic yield for such defects has not been evaluated. Here, we performed...

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PMID: 41005306
DOI: 10.1016/j.xgen.2025.101012

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