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Article

Conditional quorum-sensing induction of a cyanide-insensitive terminal oxidase stabilizes cooperating populations of Pseudomonas aeruginosa.

Nature communications - 1 Nov 2019

Yan Huicong, Asfahl Kyle L, Li Na, Sun Feng, Xiao Junwei, Shen Dongsheng, Dandekar Ajai A, Wang Meizhen

Abstract excerpt

Pseudomonas aeruginosa, an opportunistic pathogen of humans, uses quorum sensing (QS) to regulate the production of extracellular products that can benefit all members of the population. P. aeruginosa can police QS-deficient cheaters by producing hydrogen cyanide, which is also QS regulated; however, the mechanism by which cooperators selectively protect themselves from the toxicity of cyanide remained...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31676850
DOI: 10.1038/s41467-019-13013-8
PMCID: PMC6825135

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