Article
Thymus-like phenotype in benign lymphoepithelial neoplasms of salivary glands: clinicopathological and molecular characterization and reappraisal of relationship to non-sebaceous lymphadenoma.
Virchows Archiv : an international journal of pathology - 1 May 2026
Agaimy Abbas, Laco Jan, Schubart Christoph, Stoehr Robert, Tögel Lars, Ihrler Stephan
Abstract excerpt
Benign lymphoepithelial tumors of salivary glands had been restricted to sebaceous and non-sebaceous (NSLA) lymphadenomas. However, salivary neoplasms recapitulating carcinoma showing thymus-like elements (CASTLE) have been the subject of recent case reports. We reviewed clinicopathological, immunohistochemical, and molecular findings in 20 salivary gland tumors with thymus-like phenotype (18 histologically...
Topics
- Humans
- Male
- Female
- Aged
- Middle Aged
- Adult
- Aged, 80 and over
- Salivary Gland Neoplasms
- Phenotype
- Adenolymphoma
- Biomarkers, Tumor
