Article
Cutaneous Lymphadenoma Is a Distinct Trichoblastoma-like Lymphoepithelial Tumor With Diffuse Androgen Receptor Immunoreactivity, Notch1 Ligand in Reed-Sternberg-like Cells, and Common EGFR Somatic Mutations.
The American journal of surgical pathology - 1 Oct 2021
Monteagudo Carlos, Fúnez Rafael, Sánchez-Sendra Beatriz, González-Muñoz José F, Nieto Gema, Alfaro-Cervelló Clara, Murgui Amelia, Barr Ronald J
Abstract excerpt
The term "cutaneous lymphadenoma" was coined in this journal for an unusual lymphoepithelial cutaneous adnexal neoplasm, possibly with immature pilosebaceous differentiation. Some authors further proposed that cutaneous lymphadenoma was an adamantinoid trichoblastoma. However, although a hair follicle differentiation is widely accepted, the fact that this is a lymphoepithelial tumor is not appropriately explained...
Topics
- Adenolymphoma
- Adult
- Aged
- Biomarkers, Tumor
- DNA Mutational Analysis
- Epithelial Cells
- ErbB Receptors
- Female
- Hair Follicle
- High-Throughput Nucleotide Sequencing