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Article

NUT Carcinoma of the Salivary Glands: Clinicopathologic and Molecular Analysis of 3 Cases and a Survey of NUT Expression in Salivary Gland Carcinomas.

The American journal of surgical pathology - 1 Jul 2018

Agaimy Abbas, Fonseca Isabel, Martins Carmo, Thway Khin, Barrette Ryan, Harrington Kevin J, Hartmann Arndt, French Christopher A, Fisher Cyril

Abstract excerpt

NUT carcinoma (NC) represents a rare subset of highly aggressive poorly differentiated carcinomas characterized by rearrangement of the NUT (aka NUTM1, nuclear protein in testis) gene, most commonly fused to BRD4. Originally described as a mediastinal/thymic malignancy, NC has been reported at a variety of anatomic regions including the upper and lower aerodigestive tract. To date, only 7 NC cases of probable...

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Source

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Identifiers

PMID: 29649019
DOI: 10.1097/PAS.0000000000001046
PMCID: PMC6010176

Genes

BRD4
NUTM1

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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