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Article

CRISPR-mediated modulation of EGFR signaling in lung cancer.

Cancer treatment and research communications - 1 Jan 2025

Tabibian Mobina, Motevaseli Elahe, Ghafouri-Fard Soudeh

Abstract excerpt

Lung cancer is among the most common cancers and the leading source of cancer death. Inhibition of EGFR signaling by small-molecule tyrosine kinase inhibitors and monoclonal antibodies has provided new opportunities for treatment of this type of cancer. However, prognosis remained unfavorable due to the incidence of intrinsic or attained resistance. The advent of CRISPR/Cas9 technology has offered additional...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40907203
DOI: 10.1016/j.ctarc.2025.100992

Genes

EGFR

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