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Article

Antioxidant network-based signatures cluster glioblastoma into distinct redox-resistant phenotypes.

Frontiers in immunology - 1 Jan 2024

Yang Yihan, More Sanket, De Smet Frederik, De Vleeschouwer Steven, Agostinis Patrizia

Abstract excerpt

Introduction: Aberrant reactive oxygen species (ROS) production is one of the hallmarks of cancer. During their growth and dissemination, cancer cells control redox signaling to support protumorigenic pathways. As a consequence, cancer cells become reliant on major antioxidant systems to maintain a balanced redox tone, while avoiding excessive oxidative stress and cell death. This concept appears especially...

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Identifiers

PMID: 38698847
DOI: 10.3389/fimmu.2024.1342977
PMCID: PMC11063242

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C2
C3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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