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Revolutionizing cardiac fibrosis treatment: the potential of personalized CAR T-cell therapy

22 Aug 2025

Abstract excerpt

Cardiac fibrosis, a condition characterized by the deposition of excess collagen in the cardiac tissue, is a major complication of various cardiovascular diseases, including myocardial infarction, hypertension, and different types of cardiomyopathies. CAR T-cell therapy, a form of immunotherapy that involves the genetic modification of T cells to recognize and target specific antigens, has shown promise in the...

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PMID: 40847431
DOI: 10.1186/s40959-025-00367-w

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