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Article

Revolutionizing Antifibrinolytic Therapy: Personalized Strategies for Total Hip Arthroplasty Patients Who Have Divergent Fibrinolytic Responses.

The Journal of arthroplasty - 1 Nov 2025

Luo Xuefeng, Liu Jiacheng, Zhang Tao, Su Bao, Huang Wei, Lei Yiting

Abstract excerpt

BACKGROUND: While empirical antifibrinolysis immediately postsurgery effectively reduces postoperative hidden blood loss (HBL), the emerging concept of fibrinolytic phenotypes may challenge this routine practice. This randomized controlled trial investigated the efficacy of using the fibrinolytic marker LY30 to distinguish divergent phenotypes following total hip arthroplasty (THA), thereby enabling personalized...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40846122
DOI: 10.1016/j.arth.2025.08.029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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