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Article

A Phenotype-driven strategy for bilateral VATS in severe factor VII deficiency: securing hemostasis without complete parameter correction.

Journal of cardiothoracic surgery - 25 Apr 2026

Yao Yun-Peng, Bian Hong-Chun, Liu Yv, Chen Zhao, Xin Ning, Xu Rui-Xin

Abstract excerpt

BACKGROUND: Perioperative management for severe Factor VII (FVII) deficiency in thoracic surgery typically aims to reduce bleeding risk by correcting coagulation parameters with factor replacement—a strategy limited by cost, thrombotic risk, and availability. This report describes a phenotype-driven strategy, guided by a prior uneventful invasive procedure, that enabled safe surgery without routine factor...

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Identifiers

PMID: 42035202
DOI: 10.1186/s13019-026-04052-6
PMCID: PMC13255272

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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